The comfortable-clipped sequences that overhang the breakpoint are collapsed into a consensus sequence employing a a number of sequence alignment (MSA) delivered during the seqAn library [27]. Wham applies three filters towards the consensus sequences. Breakpoints usually are not noted in situations
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Wham is suitable for paired-end Illumina libraries with common insert sizes (~300bp-500bp). Wham integrates mate-pair mapping, split read mapping, gentle-clipping, choice alignment and consensus sequence primarily based proof to predict SV breakpoints with single-nucleotide accuracy. Wham generates
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